Intracellular invasion and survival of Brucella neotomae, another possible zoonotic Brucella species
نویسندگان
چکیده
منابع مشابه
Host-parasite Relationships with Brucella Neotomae.
Gibby, Irvin W. (Cornell University Medical College, New York, N.Y.), and Anna M. Gibby. Host-parasite relationships with Brucella neotomae. J. Bacteriol. 89:9-16. 1965.-An investigation was undertaken to ascertain whether a vigorous parasitic state could be evolved by transfer procedures in the host-parasite system, Brucella neotomae versus the white mouse. Visible disease was not maintained a...
متن کاملBrucella neotomae Infection in Humans, Costa Rica
Several species of Brucella are known to be zoonotic, but B. neotomae infection has been thought to be limited to wood rats. In 2008 and 2011, however, B. neotomae was isolated from cerebrospinal fluid of 2 men with neurobrucellosis. The nonzoonotic status of B. neotomae should be reassessed.
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Brucella organisms are pathogens that ultimate goal is to propagate in their preferred niche, the cell. Upon cell contact the bacteria is internalized via receptor molecules by activating small GTPases of the Rho subfamily and by a moderate recruitment of actin filaments. Once inside cells, Brucella localizes in early phagosomes, where it avoids fusion with late endosomes and lysosomes. These e...
متن کاملMetabolic studies on Brucella neotomae (Stoenner and Lackman).
Stoenner and Lackman (1957) isolated an organism from the wood rat Neotoma lepida and, on the basis of its behavior on differential dye media, CO2 requirements, and H2S production, regarded it as a new species of Brucella, for which they proposed the name Brucella neotomae. Although recognition of a new species may be justified on the basis of these conventional techniques, it was considered ad...
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With the aim of developing quantitative PCR methods for the detection and differentiation of Brucella species, the genomes of Brucella ceti, Brucella inopinata, Brucella netotomae, and Brucella suis biovar 4 were sequenced and analyzed.
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2019
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0213601